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MERS is a novel clinic-radiological syndrome first described in Japan. A transient splenial lesion with reduced diffusion that appears as a high signal intensity in diffusion-weighted MRI is the main diagnostic feature. Rotavirus is one of the most common agents associated with MERS, although our knowledge only one previous case has been reported from Europe. The majority of patients appear to achieve full recovery following rotavirus-associated MERS, irrespective of treatment. This case, together with other published reports, supports the hypothesis that rotavirus-associated MERS is unlikely to be the result of direct viral invasion of the CNS. It has been suggested that MERS may caused by intra-myelinic axonal oedema or local inflammatory cell infiltration; however, the pathogenesis remains incompletely understood. |
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children
corpus callosum
corpus callosum,lesion of
diarrhea
differential diagnosis
encephalopathy
fever
gastroenteritis
gastrointestinal disease,neurologic complications
headache
hyponatremia
level of consciousness,decreased
mental status,abnormal
MERS
MRI,abnormal
MRI,diffusion weighted
MRI,disappearing lesion on
nausea and vomiting
prognosis
reversible neurologic disorder
reversible splenial lesion syndrome
rotavirus
seizure
splenium of corpus callosum
symmetric brain lesions
viral infection
viral infection,CNS
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